日本关东化学 Kanto Nickel Catalyst for Direct Cross Coupling（Ni-dcype）

Cross coupling reaction is one of the useful reactions in the organic syntheses and is

widely used for the syntheses of pharmaceuticals, agricultural materials, bioactive com-

pounds, and organic electrochemical materials.

Our company launched a new Ni catalyst (Ni-dcype) developed by Prof. Kenichiro Itami,

Prof. Junichiro Yamaguchi of Institute of Transformative Bio-Molecules (WPI-ItbM),

Nagoya University. Cross coupling products are obtainable in high yields using this cata-

lyst by the reaction of heteroaromatic compounds with phenol derivatives, aromatic

compounds bearing ester functions, enol compounds, or α,β-unsaturated esters.

1,2‐Bis(dicyclohexylphosphino)ethane]dicarbonylnickel    CAS No：141974-66-5

Product No.	04870-65
Product name	1,2‐Bis(dicyclohexylphosphino)ethane]dicarbonylnickel(0)
Grade	Organics
Purity	97.0%~103.0%
Package	500mg
Stock	20<=

Byname Ｎｉ‐ｄｃｙｐｅ
Formula (C6H11)2PCH2CH2P(C6H11)2Ni(CO)2
Formula weight ：537.32
CAS No：141974-66-5

Advantages of this reaction

■New type of cross coupling reaction, which is not conducted with the

previous catalysts

■Green reaction without using of oraganometallic substrates and organic

halogen compounds

■Ubiquitous Ni catalyst (non-use Pd)

Related products

1,2-Bis(dicyclohexylphosphino)ethane  CAS：23743-26-2  FW：422.60

04874-45    04874-65

Bis(1,5-cyclooctadiene)nickel  CAS：1295-35-8  FW：275.06

04875-65    04875-55

Dicarbonylbis(triphenylphosphine)nick  CAS：13007-90-4  FW：639.28

11235-55    5 g

References

1)Amaike, K.; Muto, K.; Yamaguchi, J.; Itami, K. J. Am. Chem. Soc. 2012, 134, 13573.

2)Muto, K.; Yamaguchi, J.; Itami, K. J. Am. Chem. Soc. 2012, 134, 169.

3)Meng, L.; Kamada, Y.; Muto, K.; Yamaguchi, J.; Itami, K. Angew. Chem. Int. Ed. 2013, 52, 10048.