属性
生物来源
mouse

质量水平
100

抗体形式
purified immunoglobulin

antibody product type
primary antibodies

克隆
Fmc-7, monoclonal

species reactivity
human

technique(s)
flow cytometry: suitable
western blot: suitable

同位素/亚型
IgMκ

运输
wet ice

Gene Information

human … MS4A1(931)

说明
一般描述
B cells are lymphocytes that play a large role in the humoral immune response as opposed to the cell-mediated immune response that is governed by T cells. The principal function of B cells is to make antibodies against soluble antigens. B cells are an essential component of the adaptive immune system. FMC-7 B-Cell Lymphocyte Marker is a 105 kDa B cell restricted antigen which is expressed on about 50% of adult human peripheral blood B cells. Upon in vivo B cell activation FMC7 expression initially increases. B cells involved in antibody secretion have lost the FMC7 determinant. The monoclonal antibody FMC7 delineates a subpopulation of B lymphocytes in normal blood. Expression of the antigen recognized by FMC7 appears to be maturation-linked, and it serves to distinguish different types of B cell leukemia.
免疫原
HRIK [human B-lymphoblastoid cell] corresponding to human Fmc-7 (B-Cell Lymphocyte Marker).
应用
Flow Cytometry Analysis: 4.0 μg of this antibody detected Fmc-7 (B-Cell Lymphocyte Marker) in peripheral blood mononuclear cells.
This Anti-Fmc-7 (B-Cell Lymphocyte Marker) antibody is validated for use in WB, FC for the detection of Fmc-7 (B-Cell Lymphocyte Marker).
质量
Evaluated by Western Blotting in THP-1 cell lysate.

Western Blotting Analysis: 2.0 μg/mL of this antibody detected Fmc-7 (B-Cell Lymphocyte Marker) in 10 μg of THP-1 cell lysate.
目标描述
~105 kDa observed. Uncharacterized band(s) may appear in some lysates.
外形
Ammonium Sulfate
Format: Purified
Purified mouse monoclonal IgMκ in buffer containing 0.1M Tris, 10mM Glycine, 0.5M NaCl, and 0.1% Sodium Azide.
其他说明
Concentration: Please refer to lot specific datasheet.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.