标签归档：9011-18-1

现货 MP,硫酸钠葡聚糖(DSS),肠炎造模级,0216011080,9011-18-1

发表于由

葡聚糖硫酸钠（Dextran Sulfate Sodium Salt,DSS）是一种聚阴离子衍生物，是目前肠炎造模研究领域金标准。MP Biomedicals公司生产的独特的葡聚糖硫酸钠是同行科学评议刊物里应用最多的一种产品，迄今为止，有超过8000篇科学文献引用，有效性得到了业界广泛认可。

Application Notes

葡聚糖硫酸钠 (DSS)是最常见、最有效的诱导溃疡性结肠炎的药物之一。DSS结肠炎模型也被广泛应用于研究结肠癌的发展与结肠炎症的关系，例如对长期溃疡性结肠炎的研究。我公司可提供结肠炎模型创建试剂的金标准-结肠炎级葡聚糖硫酸钠(分子量36,000-50,000) 和结肠致癌物偶氮甲烷 (AOM)因其高效性而成为科学文献中应用最广泛的DSS产品之一。在过去的15年中，超过8000份科研文献引用了我公司的DSS产品。

Usage Statement

Unless specified otherwise, MP Biomedical’s products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Key Applications

Acute/ Chronic Ulcerative Colitis Model Induction, Chronic Colitis Associated Colon Cancer Model Induction

SKU 02160110-CF
Alternate Names DSS, Dextran Sodium Sulfate
Application Notes 葡聚糖硫酸钠 (DSS)是最常见、最有效的诱导溃疡性结肠炎的药物之一。DSS结肠炎模型也被广泛应用于研究结肠癌的发展与结肠炎症的关系，例如对长期溃疡性结肠炎的研究。我公司可提供结肠炎模型创建试剂的金标准-结肠炎级葡聚糖硫酸钠(分子量36,000-50,000) 和结肠致癌物偶氮甲烷 (AOM)因其高效性而成为科学文献中应用最广泛的DSS产品之一。在过去的15年中，超过8000份科研文献引用了我公司的DSS产品。
Base Catalog Number 160110
Boiling Point 310 ° C
CAS # 9011-18-1
Grade Colitis Grade
Melting Point 92 ° C
Molecular Weight 36,000 – 50,000 Da
Personal Protective Equipment Eyeshields, Gloves, respirator filter
pH (1% aqueous solution) 5-7.11
References Kinchen, J. Structural Remodeling of the Human Colonic Mesenchyme in Inflammatory Bowel Disease. Cell. 2018, 175, 372-386.

 

Mahalhal , A. Oral iron exacerbates colitis and influences the intestinal microbiome, PLOS ONE. 2018, 13, e0202460.

 

Dokoshi, T. Hyaluronidase inhibits reactive adipogenesis and inflammation of colon and skin. JCI Insight. 2018, 3, e12307.

 

Zhu, H. RNA virus receptor Rig-I monitors gut microbiota and inhibits colitis-associated colorectal cancer. J. Exp. Clin. Cancer Res. 2017, 36, 2.

 

Monticelli, L. IL-33 promotes an innate immune pathway of intestinal tissue protection dependent on amphiregulin–EGFR interactions. PNAS. 2015, 112, 10762-10767.
RTECS Number HH9290000
Solubility 100 mg/mL (decreases with increasing of MW)
Usage Statement Unless specified otherwise, MP Biomedical’s products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
Vapor Pressure 2.6 x 10-4 mm Hg at 25 ° C (Estimated)