S4751 硬脂酸 Grade I, ≥98.5% (capillary GC)
S4751
Sigma-Aldrich
硬脂酸
Grade I, ≥98.5% (capillary GC)
别名:1-十八碳烷酸, NSC 25956, 硬脂酸, 十八烷酸, C18:0, NSC 261168
线性分子式:CH3(CH2)16COOH
CAS号:57-11-4
分子量:284.48
Beilstein:608585
EC 号:200-659-6
EC 号:200-313-4
EC 号:202-851-5
MDL编号:MFCD03458596
MDL编号:MFCD00083496
MDL编号:MFCD00002752
MDL编号:MFCD00866498
MDL编号:MFCD00132259
PubChem化学物质编号:329824550
PubChem化学物质编号:24277932
PubChem化学物质编号:24899616
NACRES:NA.25
S4751-1G 1G? ? ?￥424.38
S4751-5G 5G? ? ?￥557.53
S4751-10G 10G? ? ￥1,081.60
S4751-25G 25G? ? ￥2,177.28
S4751-100G 100G? ?￥4,440.81
属性
测定
~99% (GC)
≥99% (HPLC)
>90% (HPLC)
≥98.5% (capillary GC)
质量水平
200
drug control
Home Office Schedule 2; stupéfiant (France); kontrollierte Droge in Deutschland; regulated under CDSA – not available from Sigma-Aldrich Canada
生物来源
synthetic
蒸汽压
1 mmHg ( 173.7 °C)
类型
Grade I
浓度
100 μg/mL
形式
solid
lyophilized powder
powder
应用
HPLC: suitable
gas chromatography (GC): suitable
溶解性
DMSO: 19 mg/mL
H2O: soluble
chloroform: 100 mg/mL, clear, colorless
分子量
1711
格式
single component solution
组成
Peptide content, ~80%
储存温度
room temp
?20°C
2-8°C
UniProt登记号
P40763
bp
361 °C (lit.)
mp
67-72 °C (lit.)
密度
0.845 g/cm3
官能团
carboxylic acid
运输
ambient
说明
Amino Acid Sequence
Ser-Leu-Met-Gln-Phe-Gly-Asn-Asn-Gly-Glu-Gly-Ala-Glu-Pro-Ser-Ala-Cys-NH2
一般描述
Quickly and effectively removes 3H, 14C, and 32P residues from glassware. For most applications, the concentrate should be diluted 1:49 with warm water.
硬脂酸是一种C18饱和脂肪酸。
应用
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Sobuzoxane was used to study the effect of topoisomerase II inhibition on expression of melanocytic antigens by tumor cells.
硬脂酸用于脂肪酸制备。
生化/生理作用
β-硬脂酸氧化生成8个FADH2（黄素腺嘌呤二核苷酸）和NADH2（烟酰胺腺嘌呤二核苷酸）分子和9个乙酰辅酶A分子。
Sobuzoxane, a dioxopiperazine, chelates metal cations and reduces the generation of free radicals due to metal-anthracycline complexes. It interacts with topoisomerase II and blocks the formation of topoisomerase II-DNA complex. Sobuzoxane effectively blocks cell proliferation and blocks cells in G2/M phase in selected human tumor cell lines. It protects cardiomyocytes from the cardiotoxicity induced by prolonged doxorubicin treatment.
Control peptide for the STAT3 rabbit polyclonal antibody.
Sobuzoxane is a DNA topoisomerase II inhibitor that induces apoptosis.
其他说明
0.5 mg net peptide/vial.
安全信息
Storage Class Code
11 – Combustible Solids
WGK
nwg
闪点(F)
Not applicable
闪点(C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves